is a risk-less method to investigate paternity during pregnancy on the basis of blood samples.
The non invasive prenatal paternity test Confidence is available as pioneering innovation in Europe and provides parents with security and comfort long before birth.
Until some years ago the only invasive method of analysing prenatal samples was after either chorionic villi sampling or amniotic puncture which both are not free of risk for the child and the mother.
We know since 2015 that the child's cells and cell-free DNA enter the mother's bloodstream during early embryogenesis. Free circulating DNA and maternal DNA are obtained from the mother's blood.
With this newly developed risk-free prenatal paternity test only blood samples from the mother and the alleged father are sufficient to prove paternity:
The Procedure
- We provide a special tube coated with a fixative for the mother's blood. 10 ml venous blood is drawn from her and 2 ml from the alleged father or alternatively 10 cut fingernails.
Arrange appointment for blood drawal, either at our lab or at your physician
- these blood vials and the corresponding documents are sent directly to our partner lab.
The Technique
uses targeted sequencing: about 500 single nucleotide polymorphisms (SNPs) are detected on the maternal, paternal DNA and the cell-free fetal DNA in maternal plasma. The technology uses state-of-the-art bioinformatic algorithms to calculate the differences in genetic profiles of father and child:
The result is a paternity index of more than 99.99% for a proven paternity or a 100% exclusion.
Performance from the 7th week of gestation onwards.
Not applicable for pregnancies with more than one fetus (except monozygotic twins) and when the mother has had a miscarriage or abortion in the year before,
nor with history of a blood transfusion or bone marrow-/ stem cell transplantation or when the mother has a tumor or preeclampsia. In rare cases, it may be necessary to take new blood samples from the mother if the concentration of fetal DNA in her blood is not sufficient for analysis. This is free of charge, but of course delays the result.
Result is given 14 days after sampling via a report.
You cannot insist on a definite date of result because biomedical analysis can take 1-2 days longer than expected.
Withdrawal of the analysis: if analysis has begun after 2 days, full price is charged.
50% off the price in case of cancelling within 2 days after the samples have been received in our partner laboratory.